Labmedics supply platelet technologies that have revolutionized platelet function testing in clinical and research laboratories. Providing the most comprehensive platelet tests available from any one company, CHRONO-LOG® Platelet Aggregation and Secretion methodologies have been reliable tools in the diagnosis of platelet function defects, monitoring of anti-platelet drugs and assisting researchers in developing new therapies.

Hemostasis

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Chrono-log

Celebrating 50 YEARS in the platelet testing field, Chrono-log was one of the first companies to manufacture the Platelet Aggregometer based on the Born method of measuring platelet aggregation in Platelet-Rich-Plasma [PRP] samples. Chrono-log has continued to specialize in Platelet Function Testing and was the first company to produce the Lumi-Aggregometer. Lumi-Aggregation, the measurement of ATP Release from the dense granules, provides the ability to perform a Secretion Study simultaneously with platelet aggregation in the same test sample. 

Products

Chrono-log Model 700

MODEL 700

The Chrono-log Model 700 - The only commercially available Whole Blood/Optical
Lumi-Aggregometer available in a two or four channel configuration. 
Chrono-log WBA

WBA SYSTEMS

Available in two (2) or four (4) channel configurations … providing testing of platelet function in whole blood samples utilizing either reusable or disposable probes.
Chrono-log Model 490 4+4

MODEL 490 4+4

8-Channel optical aggregation system ideal for small samples as only 250 µL of PRP is required per test with improved self-calibration of optical circuits.

Reagents

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CHRONO-PAR ADP

Each vial contains 2.5mg of lyophilized adenosine diphosphate. Performs 500 to 1,000 tests in PRP or Whole Blood samples.

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CHRONO-PAR ARACHIDONIC ACID

Each vial contains a minimum of 10mg of Arachidonic Acid, purity better than 99%. Included is a vial containing 100mg bovine albumin, fraction V powder, 96% to 99% purity. Performs 70 to 140 tests in PRP or Whole Blood samples.

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CHRONO-PAR ATP STANDARD

For the quantitation of ATP Release. Supplied as 2 μmole of lyophilized adenosine 5' triphosphate. 5 μL added to any size test sample provides a 2 nmole standard.

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CHRONO-PAR COLLAGEN

Each vial contains 1mg of native Collagen fibrils (type I) from equine tendons suspended in isotonic glucose solution of pH 2.7. Performs 500 to 1,000 tests in PRP or Whole Blood samples.

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CHRONO-PAR EPINEPHRENE

Lyophilized preparation of 1-Epinephrine bitartarate with stabilizers. Performs 1000 or more tests in PRP samples.

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CHRONO-LUME

Reagent for measurement of ATP release. Each vial contains 0.2 mg luciferin, 22,000 units d-luciferase plus magnesium sulfate, human serum albumin, stabilizers and buffer. Kit includes 4 vials of CHRONO- LUME plus a vial of lyophilized adenosine 5' triphosphate for use as an ATP Standard. Performs 50 to 100 tests in PRP or Whole Blood samples.

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CHRONO-PAR THROMBIN

Each vial contains a minimum of 10 units of lyophilized Thrombin from human plasma. Performs 10 to 20 tests in PRP or Whole Blood samples.

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CHRONO-PAR RISTOCETIN

Each vial contains 62.5mg of stabilized freeze dried Ristocetin. Performs 62 to 125 tests in PRP or Whole Blood samples.

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Ristocetin CoFactor Assay

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RISTOCETIN COFACTOR ASSAY KIT (von Willebrand Factor Assay)

For use in the quantitative determination of Factor VIII Ristocetin Cofactor Activity in citrated plasma. The following Materials included provide volumes sufficient to run 15 determinations: Ristocetin, 7.5 mg/vial; Lyophilized Human Platelets, 6 mL; von Willebrand Reference Plasma, Normal, 1.0 mL; von Willebrand Reference Plasma, Deficient, 0.5 mL; Tris Buffered Saline (TBA) 12 mL.

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vW REFERENCE PLASMA NORMAL 1mL

For use in the quantitative determination of Factor VIII Ristocetin Cofactor Activity in citrated plasma. Each vial contains dried human plasma standardized for Ristocetin Cofactor Activity, 1.0 mL.

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RISTOCETIN, 7.5mg/vial

For use in the quantitative determination of Factor VIII Ristocetin Cofactor Activity in citrated plasma. Each vial contains 7.5 mg of freeze dried Ristocetin for performing up to 15 determinations @ 1.0 mg/mL.

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vW REFERENCE PLASMA DEFICIENT .5mL

For use in the quantitative determination of Factor VIII Ristocetin Cofactor Activity in citrated plasma. Each vial contains dried human plasma derived from human congenital von Willebrand patients, 0.5 mL.

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LYOPHILIZED HUMAN PLATELETS 6mL, TRIS BUFFERED SALINE 12mL

For use in the quantitative determination of Factor VIII Ristocetin Cofactor Activity in citrated plasma. Each vial provides 6 mL of Platelets following reconstitution with Tris Buffered Saline (TBS) for performing up to 15 determinations.

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TRI-BUFFERED SALINE 12mL

For use in the reconstitution of lyophilized Platelets, used in the quantitative determination of Factor VIII Ristocetin Cofactor Activity in citrated plasma. Each vial contains 12 mL Tris Buffered Saline (TBS).

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HEMOSTASIS REFERENCE PLASMA 1mL

For use as a Reference Plasma in the quantitative determination of Factor VIII Ristocetin Cofactor Activity in citrated plasma. Each vial contains 1.0 mL of dried plasma prepared from a pool of Normal Human Plasma. All analytes are in the Normal Range.

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HEMOSTASIS REFERENCE PLASMA ABNORMAL 1mL

For use as an Abnormal Reference Plasma in the quantitative determination of Factor VIII Ristocetin Cofactor Activity in citrated plasma.  Each vial contains 1.0 mL of dried plasma prepared from a pool of Normal Human Plasma. All analytes are adjusted to be in the Abnormal Range.

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Supplies